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In clinical studiesthere was no age-related change in the efficacy or safety profile of the drugWhen advanced age is associated with decrease in renal functionhoweverthe guidelines set out in Table 1 should be used to determine the starting dose of ZestrilThereafterthe dosage should be adjusted according to the blood pressure response.
For the treatment of high blood pressureit may take 2 to 4 weeks before you get the full benefit of this medicationFor the treatment of heart failureit may take weeks to months before you get the full benefit of this medicationTell your doctor if your condition does not get better or if it gets worsefor exampleyour blood pressure readings remain high or increase
Too much sweatingdiarrheaor vomiting may cause loss of too much body waterdehydrationand increase your risk of lightheadednessReport prolonged diarrhea or vomiting to your doctorBe sure to drink enough fluids to prevent dehydration unless your doctor directs you otherwise.
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zestril is indicated to reduce signs and symptoms of systolic heart failure see clinical studies .