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The following adverse reactions are described in more detail in the WARNINGS AND PRECAUTIONS section of the label:

Because valproate reduces the clearance of lamotriginethe dosage of lamotrigine in the presence of valproate is less than half of that required in its absencesee DOSAGE AND ADMINISTRATIONDRUG INTERACTIONS

Safety and effectiveness of LAMICTAL have not been established1as initial monotherapy2for conversion to monotherapy from AEDs other than carbamazepinephenytoinphenobarbitalprimidoneor valproateor3for simultaneous conversion to monotherapy from 2 or more concomitant AEDs.

A therapeutic plasma concentration range has not been established for lamotrigineDosing of LAMICTAL should be based on therapeutic responsesee CLINICAL PHARMACOLOGY

Lamictal also passes into breast milk and may cause side effects in your child if you breastfeedTalk to your doctor about the best way to feed your child if you take Lamictal.

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