Ethionamide and prothionamide are thioamides used as second-line antituberculosis drugs for treatment of multi-drug resistant tuberculosis.
Information about Ethionamide.
CommentsAdditional drug/s should be given with this drug to treat patients with susceptible strains of tuberculosisMalabsorption syndrome may occur in patients who adhere to treatment but fail to appropriately respondand may be present in patients with concurrent HIV infectionTherapeutic drug monitoring should be considered in patients with malabsorption syndromeThe duration of treatment should be based on clinical responseincluding permanent bacteriological conversion and maximal clinical improvementThe American Academy of PediatricsAAPrecommends once a day treatment with isoniazidrifampinand pyrazinamide for 2 months in patients with meningitis caused by M tuberculosisand once a day treatment with isoniazid and rifampin for 9 to 12 months in patients with meningitis caused by Mycoplasma bovis.
Ethionamide is used with other medications to treat tuberculosisTBEthionamide is an antibiotic and works by stopping the growth of bacteria.
UsesTreatment of active tuberculosis in patients with Mycobacterium tuberculosis resistant to isoniazid or rifampinTreatment of active tuberculosis in patients infected with M tuberculosis when there is intolerance to other drugs.
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