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The CHMPin light of the data submitted and the scientific discussion within the Committeewas of the opinion that the SmPCslabelling and package leaflets should be harmonised across the EU.
For use as first-line treatment of postmenopausal women with hormone receptor positive or hormone receptor unknown locally advanced or metastatic breast cancerFemara is also indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy2.5 mg tablet orally administered once a day without regard to meals.
Femara is used in postmenopausal women because aromatase is involved in producing most of the oestrogen in this population.
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there were fewer multiple pregnancies in women who used femara 3.