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Literature reports suggest apparent association between use of corticosteroids and left ventricular free wall rupture after recent myocardial infarctiontherapy with corticosteroids should be used with great caution in these patients.
Corticosteroids may exacerbate systemic fungal infectionsnot for use in presence of such infections unless needed to control life-threatening drug reactionsconcomitant use of amphotericin B and hydrocortisone followed by cardiac enlargement and congestive heart failure reported.
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